专利名称：Substances and Pharmaceutical
Compositions for the Inhibition of
Glyoxalases and Their Use Against Bacteria
发明人：Klaus Huse,Gerd Birkenmeier,Monika
Birkenmeier
申请号：US12159633申请日：20060413
公开号：US20100204161A1公开日：20100812
摘要：The present invention pertains to substances of the formula (I) wherein X is O orS; and R1-R4 are defined in the claims as inhibitors of glyoxalase I and/or II,
pharmaceutical compositions comprising one or more compounds according to formula(I) and the use of one or more compounds according to formula (I) for the treatment ofdiseases associated with increased glycolytic metabolism. In one embodiment, thedisease is a bacterial infection.
申请人：Klaus Huse,Gerd Birkenmeier,Monika Birkenmeier
地址：Markkleeberg DE,Leipzig DE,Leipzig DE
国籍：DE,DE,DE
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