CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDRO

专利名称：CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1

发明人：CLAREMON, David, A.,ZHUANG,

Linghang,LEFTHERIS, Katerina,TICE, Colin,M.,XU, Zhenrong,YE, Yuanjie,SINGH, Suresh,B.,CACATIAN, Salvacion,ZHAO,Wei,HIMMELSBACH, Frank

申请号：EP09739203.9申请日：20090430公开号：EP2300461B1公开日：20130417

摘要：This invention relates to novel compounds of the Formula Ik, Im1, Im2, Im5, In1,In2, In5, lo1, lo2, lo5, Ip1, Ip3, pharmaceutically acceptable salts thereof, and

pharmaceutical compositions thereof, which are useful for the therapeutic treatment ofdiseases associated with the modulation or inhibition of 11 β-HSD1 in mammals. Theinvention further relates to pharmaceutical compositions of the novel compounds andmethods for their use in the reduction or control of the production of Cortisol in a cell orthe inhibition of the conversion of cortisone to Cortisol in a cell.

申请人：VITAE PHARMACEUTICALS INC,BOEHRINGER INGELHEIM INT

地址：US,DE

国籍：US,DE

代理机构：Simpson, Mark Geoffrey

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